The unique composition of Indian gut microbiome, gene catalogue, and associated fecal metabolome deciphered using multi-omics approaches | Zendy

Darshan B. Dhakan | Zendy; Abhijit Maji | Zendy; Ashok Sharma | Zendy; Rituja Saxena | Zendy; Joby Pulikkan | Zendy; Tony Grace | Zendy; Andrés Gómez | Zendy; Joy Scaria | Zendy; Katherine R. Amato | Zendy; Vineet K. Sharma | Zendy

Open Access

The unique composition of Indian gut microbiome, gene catalogue, and associated fecal metabolome deciphered using multi-omics approaches

Author(s) -

Darshan B. Dhakan,

Abhijit Maji,

Ashok Sharma,

Rituja Saxena,

Joby Pulikkan,

Tony Grace,

Andrés Gómez,

Joy Scaria,

Katherine R. Amato,

Vineet K. Sharma

Publication year - 2019

Publication title -

gigascience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.947

H-Index - 54

ISSN - 2047-217X

DOI - 10.1093/gigascience/giz004

Subject(s) - metabolome , microbiome , omics , gut microbiome , metabolomics , computational biology , biology , feces , bioinformatics , microbiology and biotechnology

Metagenomic studies carried out in the past decade have led to an enhanced understanding of the gut microbiome in human health; however, the Indian gut microbiome has not been well explored. We analyzed the gut microbiome of 110 healthy individuals from two distinct locations (North-Central and Southern) in India using multi-omics approaches, including 16S rRNA gene amplicon sequencing, whole-genome shotgun metagenomic sequencing, and metabolomic profiling of fecal and serum samples.

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