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Tracking the NGS revolution: managing life science research on shared high-performance computing clusters
Author(s) -
Martin Dahlö,
Douglas G. Scofield,
Wesley Schaal,
Ola Spjuth
Publication year - 2018
Publication title -
gigascience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.947
H-Index - 54
ISSN - 2047-217X
DOI - 10.1093/gigascience/giy028
Subject(s) - computer science , data science , set (abstract data type) , database , programming language
Next-generation sequencing (NGS) has transformed the life sciences, and many research groups are newly dependent upon computer clusters to store and analyze large datasets. This creates challenges for e-infrastructures accustomed to hosting computationally mature research in other sciences. Using data gathered from our own clusters at UPPMAX computing center at Uppsala University, Sweden, where core hour usage of ∼800 NGS and ∼200 non-NGS projects is now similar, we compare and contrast the growth, administrative burden, and cluster usage of NGS projects with projects from other sciences.

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