Giardia secretome highlights secreted tenascins as a key component of pathogenesis | Zendy

Audrey Dubourg | Zendy; Dong Xia | Zendy; John P Winpenny | Zendy; Suha Al Naimi | Zendy; Maha Bouzid | Zendy; Darren W. Sexton | Zendy; Jonathan M. Wastling | Zendy; Paul R. Hunter | Zendy; Kevin M. Tyler | Zendy

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Giardia secretome highlights secreted tenascins as a key component of pathogenesis

Author(s) -

Audrey Dubourg,

Dong Xia,

John P Winpenny,

Suha Al Naimi,

Maha Bouzid,

Darren W. Sexton,

Jonathan M. Wastling,

Paul R. Hunter,

Kevin M. Tyler

Publication year - 2018

Publication title -

gigascience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.947

H-Index - 54

ISSN - 2047-217X

DOI - 10.1093/gigascience/giy003

Subject(s) - pathogenesis , component (thermodynamics) , key (lock) , secretory component , computational biology , microbiology and biotechnology , biology , computer science , immunology , ecology , antibody , physics , thermodynamics

Giardia is a protozoan parasite of public health relevance that causes gastroenteritis in a wide range of hosts. Two genetically distinct lineages (assemblages A and B) are responsible for the human disease. Although it is clear that differences in virulence occur, the pathogenesis and virulence of Giardia remain poorly understood.

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