NanoSim: nanopore sequence read simulator based on statistical characterization | Zendy

Chen Yang | Zendy; Justin Chu | Zendy; René L. Warren | Zendy; İnanç Birol | Zendy

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NanoSim: nanopore sequence read simulator based on statistical characterization

Author(s) -

Chen Yang,

Justin Chu,

René L. Warren,

İnanç Birol

Publication year - 2017

Publication title -

gigascience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.947

H-Index - 54

ISSN - 2047-217X

DOI - 10.1093/gigascience/gix010

Subject(s) - nanopore , computer science , sequence (biology) , characterization (materials science) , nanopore sequencing , computational biology , nanotechnology , biology , dna sequencing , materials science , genetics , dna

The MinION sequencing instrument from Oxford Nanopore Technologies (ONT) produces long read lengths from single-molecule sequencing - valuable features for detailed genome characterization. To realize the potential of this platform, a number of groups are developing bioinformatics tools tuned for the unique characteristics of its data. We note that these development efforts would benefit from a simulator software, the output of which could be used to benchmark analysis tools.

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