A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay | Zendy

MarkAnthony Bray | Zendy; Sigrun Gustafsdottir | Zendy; Mohammad Hossein Rohban | Zendy; Shantanu Singh | Zendy; Vebjorn Ljosa | Zendy; Katherine L Sokolnicki | Zendy; Joshua A. Bittker | Zendy; Nicole E. Bodycombe | Zendy; Vlado Dančík | Zendy; Thomas P. Hasaka | Zendy; Cindy Hon | Zendy; Melissa M. Kemp | Zendy; Kejie Li | Zendy; Deepika Walpita | Zendy; Mathias J. Wawer | Zendy; Todd R. Golub | Zendy; Stuart L. Schreiber | Zendy; Paul A. Clemons | Zendy; Alykhan F. Shamji | Zendy; Anne E. Carpenter | Zendy

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A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay

Author(s) -

MarkAnthony Bray,

Sigrun Gustafsdottir,

Mohammad Hossein Rohban,

Shantanu Singh,

Vebjorn Ljosa,

Katherine L Sokolnicki,

Joshua A. Bittker,

Nicole E. Bodycombe,

Vlado Dančík,

Thomas P. Hasaka,

Cindy Hon,

Melissa M. Kemp,

Kejie Li,

Deepika Walpita,

Mathias J. Wawer,

Todd R. Golub,

Stuart L. Schreiber,

Paul A. Clemons,

Alykhan F. Shamji,

Anne E. Carpenter

Publication year - 2017

Publication title -

gigascience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.947

H-Index - 54

ISSN - 2047-217X

DOI - 10.1093/gigascience/giw014

Subject(s) - painting , computer science , small molecule , computational biology , artificial intelligence , pattern recognition (psychology) , information retrieval , chemistry , biology , biochemistry , art , art history

Large-scale image sets acquired by automated microscopy of perturbed samples enable a detailed comparison of cell states induced by each perturbation, such as a small molecule from a diverse library. Highly multiplexed measurements of cellular morphology can be extracted from each image and subsequently mined for a number of applications.

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