Prediction of single-cell gene expression for transcription factor analysis
Author(s) -
Fatemeh Behjati Ardakani,
Kathrin Kattler,
Tobias Heinen,
Florian Schmidt,
David Feuerborn,
Gilles Gasparoni,
Konstantin Lepikhov,
Patrick Nell,
Jan G. Hengstler,
Jörn Walter,
Marcel H. Schulz
Publication year - 2020
Publication title -
gigascience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.947
H-Index - 54
ISSN - 2047-217X
DOI - 10.1093/gigascience/giaa113
Subject(s) - computational biology , transcription factor , cell type , gene expression , gene , computer science , workflow , cell , biology , regulation of gene expression , genetics , database
Single-cell RNA sequencing is a powerful technology to discover new cell types and study biological processes in complex biological samples. A current challenge is to predict transcription factor (TF) regulation from single-cell RNA data.
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