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IDseq—An open source cloud-based pipeline and analysis service for metagenomic pathogen detection and monitoring
Author(s) -
Katrina Kalantar,
Tiago Rodrigues De Carvalho,
Charles F. A. de Bourcy,
Boris Dimitrov,
Greg Dingle,
Rebecca Egger,
Julie Han,
Olivia Holmes,
Yun-Fang Juan,
Ryan J. King,
Andrey Kislyuk,
Michael F. Lin,
Maria Mariano,
Todd Morse,
Lucia Reynoso,
David Rissato Cruz,
Jonathan Sheu,
Jennifer Tang,
James Z. Wang,
Mark A. Zhang,
Emily Zhong,
Vida Ahyong,
Sreyngim Lay,
Sophana Chea,
Jennifer A. Bohl,
Jessica E. Manning,
Cristina M. Tato,
Joseph L. DeRisi
Publication year - 2020
Publication title -
gigascience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.947
H-Index - 54
ISSN - 2047-217X
DOI - 10.1093/gigascience/giaa111
Subject(s) - metagenomics , pipeline (software) , cloud computing , open source , computer science , data science , pathogen , service (business) , computational biology , biology , microbiology and biotechnology , operating system , business , gene , software , genetics , marketing
Metagenomic next-generation sequencing (mNGS) has enabled the rapid, unbiased detection and identification of microbes without pathogen-specific reagents, culturing, or a priori knowledge of the microbial landscape. mNGS data analysis requires a series of computationally intensive processing steps to accurately determine the microbial composition of a sample. Existing mNGS data analysis tools typically require bioinformatics expertise and access to local server-class hardware resources. For many research laboratories, this presents an obstacle, especially in resource-limited environments.

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