Comparative genomics and transcriptomics of 4 Paragonimus species provide insights into lung fluke parasitism and pathogenesis | Zendy

Bruce A. Rosa | Zendy; Young-Jun Choi | Zendy; Samantha N. McNulty | Zendy; Hyeim Jung | Zendy; John Martin | Zendy; Takeshi Agatsuma | Zendy; Hiromu Sugiyama | Zendy; Thanh Hoa Le | Zendy; Pham Ngoc Doanh | Zendy; Wanchai Maleewong | Zendy; David Blair | Zendy; Paul J. Brindley | Zendy; Peter Fischer | Zendy; Makedonka Mitreva | Zendy

Open Access

Comparative genomics and transcriptomics of 4 Paragonimus species provide insights into lung fluke parasitism and pathogenesis

Author(s) -

Bruce A. Rosa,

Young-Jun Choi,

Samantha N. McNulty,

Hyeim Jung,

John Martin,

Takeshi Agatsuma,

Hiromu Sugiyama,

Thanh Hoa Le,

Pham Ngoc Doanh,

Wanchai Maleewong,

David Blair,

Paul J. Brindley,

Peter Fischer,

Makedonka Mitreva

Publication year - 2020

Publication title -

gigascience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.947

H-Index - 54

ISSN - 2047-217X

DOI - 10.1093/gigascience/giaa073

Subject(s) - paragonimus , paragonimiasis , biology , paragonimus westermani , genome , genomics , zoology , gene , helminths , genetics

Paragonimus spp. (lung flukes) are among the most injurious foodborne helminths, infecting ∼23 million people and subjecting ∼292 million to infection risk. Paragonimiasis is acquired from infected undercooked crustaceans and primarily affects the lungs but often causes lesions elsewhere including the brain. The disease is easily mistaken for tuberculosis owing to similar pulmonary symptoms, and accordingly, diagnostics are in demand.

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