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De novo assembly of the cattle reference genome with single-molecule sequencing
Author(s) -
Benjamin D. Rosen,
Derek M. Bickhart,
Robert D. Schnabel,
Sergey Koren,
Christine G. Elsik,
Elizabeth Tseng,
Troy N. Rowan,
Wai Yee Low,
Aleksey V. Zimin,
Christine Couldrey,
Richard Hall,
Wenli Li,
Arang Rhie,
Jay Ghurye,
Stephanie McKay,
Françoise ThibaudNissen,
Jinna Hoffman,
Brenda M. Murdoch,
W. M. Snelling,
T. G. McDaneld,
John A. Hammond,
J.C. Schwartz,
Wilson Nandolo,
Darren E. Hagen,
Christian Dreischer,
Sebastian J. Schultheiß,
Steven Schroeder,
Adam M. Phillippy,
John B. Cole,
Curtis P. Van Tassell,
George E. Liu,
Timothy P. L. Smith,
Juan F. Medrano
Publication year - 2020
Publication title -
gigascience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.947
H-Index - 54
ISSN - 2047-217X
DOI - 10.1093/gigascience/giaa021
Subject(s) - sequence assembly , computational biology , genome , biology , reference genome , genetics , evolutionary biology , gene , gene expression , transcriptome
Major advances in selection progress for cattle have been made following the introduction of genomic tools over the past 10-12 years. These tools depend upon the Bos taurus reference genome (UMD3.1.1), which was created using now-outdated technologies and is hindered by a variety of deficiencies and inaccuracies.

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