Open AccessCognitive Function and Apolipoprotein E in Very Old Adults: Findings From the Nun Study
Author(s) -
Kathryn Riley,
David A. Snowdon,
Ann M. Saunders,
A D Roses,
James A. Mortimer,
Nishantha Nanayakkara
Publication year - 2000
Publication title -
the journals of gerontology series b
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.578
H-Index - 150
eISSN - 1758-5368
pISSN - 1079-5014
DOI - 10.1093/geronb/55.2.s69
Subject(s) - cognition , psychology , function (biology) , apolipoprotein b , medicine , neuroscience , biology , cholesterol , genetics
The epsilon4 allele of apolipoprotein E (APOE) has been associated with Alzheimer' s disease and with milder forms of cognitive impairment. We investigated the possibility that the absence of the epsilon4 allele may predict the maintenance of high cognitive function among very old individuals.
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