Open AccessRapid Buildup of Brain White Matter Hyperintensities Over 4 Years Linked to Ambulatory Blood Pressure, Mobility, Cognition, and Depression in Old Persons
Author(s) -
Leslie Wolfson,
Dorothy Wakefield,
Nicolas Moscufo,
R. F. Kaplan,
Charles B. Hall,
J.A.R. Schmidt,
Charles R.G. Guttmann,
William B. White
Publication year - 2013
Publication title -
the journals of gerontology series a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.134
H-Index - 189
eISSN - 1758-535X
pISSN - 1079-5006
DOI - 10.1093/gerona/glt072
Subject(s) - hyperintensity , depression (economics) , ambulatory , ambulatory blood pressure , cognition , medicine , blood pressure , cohort , cardiology , white matter , risk factor , cohort study , psychology , magnetic resonance imaging , psychiatry , radiology , economics , macroeconomics
Brain white matter hyperintensities (WMH) are associated with functional decline in older people. We performed a 4-year cohort study examining progression of WMH, its effects on mobility, cognition, and depression with the role of clinic and 24-hour ambulatory systolic blood pressure as a predisposing factor.
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