Open AccessPlasma Beta Amyloid Level and Depression in Older Adults
Author(s) -
Andrea L. Metti,
Jane A. Cauley,
Anne B. Newman,
Hilsa N. Ayonayon,
Lisa C. Barry,
LH Kuller,
S. Satterfield,
Eleanor M. Simonsick,
Kristine Yaffe
Publication year - 2012
Publication title -
the journals of gerontology series a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.134
H-Index - 189
eISSN - 1758-535X
pISSN - 1079-5006
DOI - 10.1093/gerona/gls093
Subject(s) - depression (economics) , hazard ratio , medicine , confidence interval , dementia , geriatric depression scale , center for epidemiologic studies depression scale , proportional hazards model , apolipoprotein e , gerontology , psychology , demography , psychiatry , disease , depressive symptoms , cognition , macroeconomics , sociology , economics
Older adults with depression have an increased risk of developing dementia. Low plasma beta-amyloid 42 (Aβ42) and Aβ42/Aβ40 have emerged as promising biomarkers of dementia. The association between depression and plasma Aβ is unclear.
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