Multiparametric NMR-Based Assessment of Skeletal Muscle Perfusion and Metabolism During Exercise in Elderly Persons: Preliminary Findings | Zendy

D Walter Wray | Zendy; Steven K. Nishiyama | Zendy; A. Monnet | Zendy; Claire Wary | Zendy; S. Duteil | Zendy; Pierre G. Carlier | Zendy; Russell S. Richardson | Zendy

Open Access

Multiparametric NMR-Based Assessment of Skeletal Muscle Perfusion and Metabolism During Exercise in Elderly Persons: Preliminary Findings

Author(s) -

D Walter Wray,

Steven K. Nishiyama,

A. Monnet,

Claire Wary,

S. Duteil,

Pierre G. Carlier,

Russell S. Richardson

Publication year - 2009

Publication title -

the journals of gerontology series a

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.134

H-Index - 189

eISSN - 1758-535X

pISSN - 1079-5006

DOI - 10.1093/gerona/glp044

Subject(s) - phosphocreatine , perfusion , skeletal muscle , medicine , endocrinology , metabolism , oxidative phosphorylation , cardiology , oxidative stress , senescence , oxidative metabolism , chemistry , energy metabolism , biochemistry

Aging is associated with a decline in exercise capacity that may be attributable to maladaptations in both skeletal muscle perfusion and metabolism; yet very little is known regarding the real-time, within-muscle interplay between these parameters during physical activity. Therefore, we utilized an unique nuclear magnetic resonance sequence to concomitantly examine changes in lower leg skeletal muscle perfusion and metabolism.

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