Association Between Inflammatory Components and Physical Function in the Health, Aging, and Body Composition Study: A Principal Component Analysis Approach | Zendy

FangChi Hsu | Zendy; Stephen B. Kritchevsky | Zendy; Y. Liu | Zendy; Alka M. Kanaya | Zendy; Anne B. Newman | Zendy; Sara Perry | Zendy; Marjolein Visser | Zendy; M. Pahor | Zendy; Tamara B. Harris | Zendy; Barbara J. Nicklas | Zendy

Open Access

Association Between Inflammatory Components and Physical Function in the Health, Aging, and Body Composition Study: A Principal Component Analysis Approach

Author(s) -

FangChi Hsu,

Stephen B. Kritchevsky,

Y. Liu,

Alka M. Kanaya,

Anne B. Newman,

Sara Perry,

Marjolein Visser,

M. Pahor,

Tamara B. Harris,

Barbara J. Nicklas

Publication year - 2009

Publication title -

the journals of gerontology series a

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.134

H-Index - 189

eISSN - 1758-535X

pISSN - 1079-5006

DOI - 10.1093/gerona/glp005

Subject(s) - association (psychology) , composition (language) , component (thermodynamics) , principal component analysis , function (biology) , psychology , computer science , biology , artificial intelligence , physics , evolutionary biology , art , thermodynamics , literature , psychotherapist

In older adults, studies demonstrate an inverse relationship between physical function and individual inflammatory biomarkers. Given that the inflammatory response is a complex system, a combination of biomarkers may increase the strength and consistency of these associations. This study uses principal component analysis to identify inflammatory "component(s)" and evaluates associations between the identified component(s) and measures of physical function.

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