Association Between Elevated suPAR, a New Biomarker of Inflammation, and Accelerated Aging | Zendy

Line Jee Hartmann Rasmussen | Zendy; Avshalom Caspi | Zendy; Antony Ambler | Zendy; Andrea Danese | Zendy; Maxwell L. Elliott | Zendy; Jesper EugenOlsen | Zendy; Ahmad R. Hariri | Zendy; HonaLee Harrington | Zendy; Renate Houts | Zendy; Richie Poulton | Zendy; Sandhya Ramrakha | Zendy; Karen Sugden | Zendy; Benjamin Williams | Zendy; Terrie E. Moffitt | Zendy

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Association Between Elevated suPAR, a New Biomarker of Inflammation, and Accelerated Aging

Author(s) -

Line Jee Hartmann Rasmussen,

Avshalom Caspi,

Antony Ambler,

Andrea Danese,

Maxwell L. Elliott,

Jesper EugenOlsen,

Ahmad R. Hariri,

HonaLee Harrington,

Renate Houts,

Richie Poulton,

Sandhya Ramrakha,

Karen Sugden,

Benjamin Williams,

Terrie E. Moffitt

Publication year - 2020

Publication title -

the journals of gerontology series a

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.134

H-Index - 189

eISSN - 1758-535X

pISSN - 1079-5006

DOI - 10.1093/gerona/glaa178

Subject(s) - biomarker , supar , inflammation , medicine , biology , receptor , genetics , urokinase receptor

To understand and measure the association between chronic inflammation, aging, and age-related diseases, broadly applicable standard biomarkers of systemic chronic inflammation are needed. We tested whether elevated blood levels of the emerging chronic inflammation marker soluble urokinase plasminogen activator receptor (suPAR) were associated with accelerated aging, lower functional capacity, and cognitive decline.

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