WormBase in 2022—data, processes, and tools for analyzing Caenorhabditis elegans | Zendy

Paul A. Davis | Zendy; Magdalena Zarowiecki | Zendy; Valerio Arnaboldi | Zendy; Andrés Becerra | Zendy; Scott Cain | Zendy; Juancarlos Chan | Zendy; Wen J. Chen | Zendy; Jaehyoung Cho | Zendy; Eduardo da Veiga Beltrame | Zendy; Stavros Diamantakis | Zendy; Sibyl Gao | Zendy; Dionysios Grigoriadis | Zendy; Christian A Grove | Zendy; Todd Harris | Zendy; Ranjana Kishore | Zendy; Tuan Anh Le | Zendy; Raymond Lee | Zendy; Manuel Luypaert | Zendy; HansMichael Müller | Zendy; Cecilia Nakamura | Zendy; Paulo Nuin | Zendy; Michael Paulini | Zendy; Mark Quinton-Tulloch | Zendy; Daniela Raciti | Zendy; Faye H. Rodgers | Zendy; Matthew Russell | Zendy; Gary Schindelman | Zendy; Archana Singh | Zendy; Tim Stickland | Zendy; Kimberly Van Auken | Zendy; Qinghua Wang | Zendy; Gary W. Williams | Zendy; A. Jordan Wright | Zendy; Karen Yook | Zendy; Matthew Berriman | Zendy; Kevin Howe | Zendy; Tim Schedl | Zendy; Lincoln Stein | Zendy; Paul W. Sternberg | Zendy

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WormBase in 2022—data, processes, and tools for analyzing Caenorhabditis elegans

Author(s) -

Paul A. Davis,

Magdalena Zarowiecki,

Valerio Arnaboldi,

Andrés Becerra,

Scott Cain,

Juancarlos Chan,

Wen J. Chen,

Jaehyoung Cho,

Eduardo da Veiga Beltrame,

Stavros Diamantakis,

Sibyl Gao,

Dionysios Grigoriadis,

Christian A Grove,

Todd Harris,

Ranjana Kishore,

Tuan Anh Le,

Raymond Lee,

Manuel Luypaert,

HansMichael Müller,

Cecilia Nakamura,

Paulo Nuin,

Michael Paulini,

Mark Quinton-Tulloch,

Daniela Raciti,

Faye H. Rodgers,

Matthew Russell,

Gary Schindelman,

Archana Singh,

Tim Stickland,

Kimberly Van Auken,

Qinghua Wang,

Gary W. Williams,

A. Jordan Wright,

Karen Yook,

Matthew Berriman,

Kevin Howe,

Tim Schedl,

Lincoln Stein,

Paul W. Sternberg

Publication year - 2022

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/iyac003

Subject(s) - caenorhabditis elegans , biology , workflow , genomics , data science , data curation , genome , alliance , caenorhabditis , computational biology , genetics , computer science , database , gene , political science , law

WormBase (www.wormbase.org) is the central repository for the genetics and genomics of the nematode Caenorhabditis elegans. We provide the research community with data and tools to facilitate the use of C. elegans and related nematodes as model organisms for studying human health, development, and many aspects of fundamental biology. Throughout our 22-year history, we have continued to evolve to reflect progress and innovation in the science and technologies involved in the study of C. elegans. We strive to incorporate new data types and richer data sets, and to provide integrated displays and services that avail the knowledge generated by the published nematode genetics literature. Here, we provide a broad overview of the current state of WormBase in terms of data type, curation workflows, analysis, and tools, including exciting new advances for analysis of single-cell data, text mining and visualization, and the new community collaboration forum. Concurrently, we continue the integration and harmonization of infrastructure, processes, and tools with the Alliance of Genome Resources, of which WormBase is a founding member.

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