"FUNDAMENTAL THEOREM" FOR TWO LOCI | Zendy

John R. Turner | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

"FUNDAMENTAL THEOREM" FOR TWO LOCI

Author(s) -

John R. Turner

Publication year - 1981

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/99.2.365

Subject(s) - linkage disequilibrium , biology , disequilibrium , covariance , genetics , fitness function , function (biology) , selection (genetic algorithm) , gamete , linkage (software) , curvature , evolutionary biology , mathematics , statistics , allele , mathematical optimization , haplotype , gene , computer science , medicine , genetic algorithm , artificial intelligence , ophthalmology , sperm , geometry

The change in mean fitness for two loci under selection can be described by four terms: (i) the variance of fitness, (ii) a weighted between-gamete covariance, (iii) a function of recombination, linkage disequilibrium and the slope of the surface of mean fitness on disequilibrium, and (iv) a function of these two parameters and the curvature of the surface. Independent derivations of this equation by different methods, although thought at one time to be in disagreement, give algebraically identical results.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research