FATE MAPPING MULTI-FOCUS PHENOTYPES
Author(s) -
Jonathan Arnold,
Douglas R. Kankel
Publication year - 1981
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/99.2.211
Subject(s) - biology , phenotype , blastoderm , genetics , abnormality , focus (optics) , mutation , cell fate determination , expression (computer science) , evolutionary biology , computational biology , embryo , gene , computer science , psychology , social psychology , physics , transcription factor , optics , embryogenesis , programming language
A central assumption used in the genetic fate mapping of anatomical sites responsible for certain mutationally induced abnormalities is that a single pair of bilaterally symmetric sites on the blastoderm gives rise to structures that control the expression of that abnormality. We report a new model that is not so constrained and test its efficacy in the analysis of several mutations that induce behavioral abnormalities.
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