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Frequency changes of alleles at eight enzyme loci were monitored in four long-term maize selection experiments. The results indicate that changes in frequencies of the alleles at these loci are associated with changes due to selection for improved grain yield. The frequencies changed more than is consistent with the hyFothesis of selective neutrality. In addition, significant deviations from a random-drift model were nearly always accompanied by significant linear tiends as would result ii allozyme frequencies respond to directional selection. Evaluations of linkages aiid linkage disequilibria in the selected populations indicate that the eight enzyme loci responded independently as selection progressed.

ALLOZYME FREQUENCY CHANGES ASSOCIATED WITH SELECTION FOR INCREASED GRAIN YIELD IN MAIZE (ZEA MAYS L.)