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DIRECTIONALITY AND NONRECIPROCALITY OF CHI-STIMULATED RECOMBINATION IN PHAGE Λ
Author(s) -
Franklin W. Stahl,
Mary M. Stahl,
Robert E. Malone,
Jean M. Crasemann
Publication year - 1980
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/94.2.235
Subject(s) - recombination , biology , genetics , recombinant dna , directionality , dna , genetic recombination , dna replication , chromosome , homologous recombination , microbiology and biotechnology , gene
Chi's are genetic elements that stimulate generalized recombination in their locale in phage λ. All Chi's, wherever located on λ's chromosome, act asymmetrically in crosses blocked in DNA replication: (1) They stimulate exchange primarily to their left on the conventional λ map, and (2) the stimulated exchange is frequently nonreciprocal, the recombinant carrying the Chi element being produced less often than the complementary product.

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