NONELECTROPHORETIC GENETIC VARIABILITY IN MOSQUITOES: POLYMORPHISM FOR TEMPERATURE-RESISTANT AND TEMPERATURE-SENSITIVE PHOSPHOGLUCOMUTASE ALLELES IN CULEX PIPIENS
Author(s) -
Rosaria Scozzari,
G. Trippa,
Vincenzo Petrarca,
Rosadele Cicchetti
Publication year - 1979
Publication title -
genetics.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
ISSN - 3049-7094
DOI - 10.1093/genetics/93.1.201
Subject(s) - biology , genetics , phosphoglucomutase , allele , loss of heterozygosity , polymorphism (computer science) , genetic variability , gene , genotype , enzyme , biochemistry
Homogenates of single individuals of two natural populations and five laboratory populations of Culex pipiens were examined by combining electrophoresis and heat denaturation studies on phosphoglucomutase (PGM). All populations showed a high degree of polymorphism for isoelectrophoretic temperature-resistant (tr) and temperature-sensitive (ts) alleles. Formal genetic data on the heat stability differences of the PGM are given. If both electrophoretic and isoelectrophoretic alleles are taken into account, the mean increase in the degree of heterozygosity is quite remarkable, i.e., about 65%.--The data are considered in relation to the biological significance that this new type of variability of structural genes could have in natural populations.
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