A MODEL ALLOWING CONTINUOUS VARIATION IN ELECTROPHORETIC MOBILITY OF NEUTRAL ALLELES | Zendy

Gary Cobbs | Zendy

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A MODEL ALLOWING CONTINUOUS VARIATION IN ELECTROPHORETIC MOBILITY OF NEUTRAL ALLELES

Author(s) -

Gary Cobbs

Publication year - 1979

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/92.2.669

Subject(s) - allele , biology , electrophoresis , genetics , recombination , mutation , electrophoretic mobility shift assay , phenotype , gene , gene expression

The infinite-sites model with no recombination is extended to include mutations that affect electrophoretic mobility. The model allows the effect of a single-site mutation to have a continuous effect on mobility. Formulae are obtained for the variance of electrophoretic mobility of alleles after an arbitrary length of time. A special case of the general model is the case of stepwise production of neutral alleles with an arbitrary number of steps.

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