A CLUSTER OF THREE GENES RESPONSIBLE FOR ALLANTOIN DEGRADATION IN SACCHAROMYCES CEREVISIAE
Author(s) -
Terrance Cooper,
Mary T. Gorski,
V Turoscy
Publication year - 1979
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/92.2.383
Subject(s) - biology , genetics , saccharomyces cerevisiae , locus (genetics) , mutant , allantoin , gene , gene cluster , chromosome , saccharomyces , biochemistry
Mutant strains of Saccharomyces cerevisiae unable to utilize allantoin as sole nitrogen murce were isolated and divided into three groups on the basis of their biochemical and genetic characteristics. The three loci associated with these mutant classes were designated dall (allantoinase minus), da12 (allantoicase minus) and da14 (allantoin transport minus). All three loci are located in a cluster that is proximal to the lysl locus on the right arm of chromosome IX. The gene order and intergenic distances were estimated to be: dall—2.5 cM—dal4—1.9cM—dal2—4.6cM—lysl.
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