A MATHEMATICALLY TRACTABLE FAMILY OF GENETIC MAPPING FUNCTIONS WITH DIFFERENT AMOUNTS OF INTERFERENCE | Zendy

Joseph Felsenstein | Zendy

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A MATHEMATICALLY TRACTABLE FAMILY OF GENETIC MAPPING FUNCTIONS WITH DIFFERENT AMOUNTS OF INTERFERENCE

Author(s) -

Joseph Felsenstein

Publication year - 1979

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/91.4.769

Subject(s) - interference (communication) , extension (predicate logic) , coincidence , simple (philosophy) , biology , argument (complex analysis) , genetics , mathematics , computer science , epistemology , medicine , computer network , channel (broadcasting) , philosophy , biochemistry , alternative medicine , pathology , programming language

By extension of the argument of KOSAMBI (1944), a family of mapping functions can be derived, which has a parameter regulating the intensity of interference. Different values of this parameter yield the HALDANE (1919) and KOSAMBI mapping functions as special cases. The parameter is the coincidence coefficient for nearby small intervals. The family includes mapping functions for negative interference. A simple rule for combining recombination fractions in adjacent intervals is also obtained.

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