AN APPARENT CONNECTION BETWEEN HISTIDINE, RECOMBINATION, AND REPAIR IN NEUROSPORA | Zendy

Dorothy Newmeyer | Zendy; Alice Schroeder | Zendy; Donna R. Galeazzi | Zendy

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AN APPARENT CONNECTION BETWEEN HISTIDINE, RECOMBINATION, AND REPAIR IN NEUROSPORA

Author(s) -

Dorothy Newmeyer,

Alice Schroeder,

Donna R. Galeazzi

Publication year - 1978

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/89.2.271

Subject(s) - neurospora crassa , neurospora , histidine , biology , mutant , genetics , recombination , meiosis , gene duplication , mutation , gene , amino acid

Two mutants of Neurospora crassa, uvs-3 and mei-3, share four properties—UV sensitivity, inhibition by histidine, meiotic blockage when homozygous, and increased duplication instability (due to mitotic crossing over, to deletions or to both). The present paper shows that a third nonallelic mutant, uvs-6, exhibits the same four properties.—Also, the instability of duplications in the absence of any UV-sensitive mutant is increased by the presence of histidine in the growth medium.

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