THE EFFECT OF INTRAGENIC RECOMBINATION ON THE NUMBER OF ALLELES IN A FINITE POPULATION | Zendy

Curtis Strobeck | Zendy; Kenneth Morgan | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

THE EFFECT OF INTRAGENIC RECOMBINATION ON THE NUMBER OF ALLELES IN A FINITE POPULATION

Author(s) -

Curtis Strobeck,

Kenneth Morgan

Publication year - 1978

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/88.4.829

Subject(s) - recombination , biology , allele , genetics , population , reciprocal , mutation , allele frequency , gene , demography , linguistics , philosophy , sociology

A two-site infinite allele model is constructed to study the effect of intragenic recombination on the number of neutral alleles and the distribution of their frequencies in a finite population. The results of theory and Monte Carlo simulation of the two-site model demonstrate that intragenic recombination significantly increases the mean and variance of the number of alleles when the rates of mutation and recombination are as large as the reciprocal of the population size. Data from natural populations indicate that this may be a significant process in generating variation and determining its distribution.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research