DISTRIBUTION AND FREQUENCY OF TANDEM DUPLICATIONS OF THE rII REGION OF BACTERIOPHAGE T4D
Author(s) -
David H Parma,
George Heath,
Chia-Chung Che,
J L Annest
Publication year - 1977
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/87.4.593
Subject(s) - extrapolation , recombination , biology , tandem , bacteriophage , genetics , genome , distribution (mathematics) , mathematics , gene , materials science , statistics , mathematical analysis , escherichia coli , composite material
Genetic analyses of 49 duplications of the rII region of bacteriophage T4D suggests that there is a non-random relationship between the end points of duplicated segments, that relaxed packaging restrictions have little if any effect on the distribution of duplications, that segregation is 3-4 times more frequent than normal recombination for the same interval, and that non-tandem duplications are rare. Extrapolation of the r1231x rJ101 cross data suggests that the minimum frequency of duplications/genome is 1.7 x 10-6, but possibly 3.4 x 10-4.
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