LINKAGE AND GENETIC MAP LENGTH IN TETRAHYMENA THERMOPHILA
Author(s) -
John W. McCoy
Publication year - 1977
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/87.3.421
Subject(s) - tetrahymena , biology , genetics , loss of heterozygosity , linkage (software) , genetic linkage , strain (injury) , genetic marker , gene mapping , evolutionary biology , allele , gene , chromosome , anatomy
The genetic map of T. thermophila has been extended with tests of over 170 marker combinations. Three linkage groups have been identified, in addition to several apparent linkages which are seen only when certain strains are used. A sampling argument was developed to estimate the total genetic map length from the observed fraction of marker combinations showing linkage. If the strain-dependent linkages are actually due to structural heterozygosity, the total map length is estimated at about 1,200 cM.
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