DRIFT OR SELECTION: A STATISTICAL TEST OF GENE FREQUENCY VARIATION OVER GENERATIONS | Zendy

Henry E. Schaffer | Zendy; Darrell G. Yardley | Zendy; Wyatt W. Anderson | Zendy

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DRIFT OR SELECTION: A STATISTICAL TEST OF GENE FREQUENCY VARIATION OVER GENERATIONS

Author(s) -

Henry E. Schaffer,

Darrell G. Yardley,

Wyatt W. Anderson

Publication year - 1977

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/87.2.371

Subject(s) - drosophila pseudoobscura , biology , allele frequency , genetics , locus (genetics) , allele , selection (genetic algorithm) , gene , population , natural selection , statistical hypothesis testing , statistics , mathematics , computer science , demography , artificial intelligence , sociology

The method used by Fisher and Ford (1947) to study the spread of a gene in a natural population has been modified to analyze the variation in allele frequencies from generation to generation in a common experimental procedure. A further analysis has been developed that is more sensitive to directional trends in the allele frequency over generations, and its use in detecting the action of directional selection on gene frequency at a locus is discussed. The power of each of these statistical tests is calculated for a number of cases, and the tests are applied to sets of isozyme data from Drosophila pseudoobscura and Zea mays.

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