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MUTAGEN SPECIFICITY IN THE INDUCTION OF CHROMOSOMAL ABERRATIONS IN SOMATIC CELLS OF DROSOPHILA MELANOGASTER
Author(s) -
Sergio Pimpinelli,
Domenico Pig,
G Santini,
Maurizio Gatti,
G. Olivieri
Publication year - 1977
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/85.2.249
Subject(s) - biology , somatic cell , drosophila melanogaster , genetics , chromosome , heterochromatin , mutagen , microbiology and biotechnology , gene , carcinogen
The distribution of chromosomal aberrations between and within chromosomes of male D. melanogaster somatic cells after treatment with UV has been analyzed.—Distribution of the breaks between chromosomes was largely nonrandom since we found a higher aberration frequency than that expected on the Y chromosome. Moreover, within the chromosomes the aberrations are clustered in the pericentromeric heterochromatic regions. The above distribution is compared with that of the breaks induced by X rays and methyl-methane-sulphonate (MMS) which were distributed in a different pattern.

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