TERMINAL REDUNDANCY HETEROZYGOTES INVOLVING THE FIRST-STEP-TRANSFER REGION OF THE BACTERIOPHAGE T5 CHROMOSOME | Zendy

David A. Fischhoff | Zendy; Douglas J. MacNeil | Zendy; Nancy Kleckner | Zendy

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TERMINAL REDUNDANCY HETEROZYGOTES INVOLVING THE FIRST-STEP-TRANSFER REGION OF THE BACTERIOPHAGE T5 CHROMOSOME

Author(s) -

David A. Fischhoff,

Douglas J. MacNeil,

Nancy Kleckner

Publication year - 1976

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/82.2.145

Subject(s) - biology , genetics , loss of heterozygosity , heterozygote advantage , terminal (telecommunication) , bacteriophage , gene , redundancy (engineering) , genome , chromosome , genotype , allele , escherichia coli , telecommunications , computer science , operating system

Individual progeny of two-factor crosses between A1am and A2am T5 phages give rise to bursts containing more than one type of plaque. The simplest explanation for these mixed bursts is that the A1 and A2 genes are located within the terminally repeated portion of the T5 genome and that the mixed bursts are made by "terminal redundancy heterozygotes". The observation of genetic heterozygosity means that the A1 and A2 genes are repeated intact. This implies that the terminal segments of T5 are genetically interchangeable.

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