ON INVERTED REPEAT SEQUENCES IN CHROMOSOMAL DNA | Zendy

Bruce Wallace | Zendy; Thomas L Kass | Zendy

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ON INVERTED REPEAT SEQUENCES IN CHROMOSOMAL DNA

Author(s) -

Bruce Wallace,

Thomas L Kass

Publication year - 1976

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/82.1.139

Subject(s) - biology , palindrome , genetics , gene , dna , transcription (linguistics) , inverted repeat , palindromic sequence , microbiology and biotechnology , genome , linguistics , philosophy

It is suggested that chromosomal DNA should contain a class of palindromic reverse repeats, comparable in number to that of genes themselves, which are formed as follows: (1) a transcription-termination signal that follows the gene plus (on the complementary strand and located as near to the "anti-gene" as possible); (2) a second termination signal which actively prevents the accidental transcription of the anti-gene. Thus, the adjacent termination-anti-termination region of one strand would complement the anti-termination-termination region of the other.

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