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EVIDENCE OF PREFERENTIAL PAIRING OF CHROMOSOMES AT MEIOSIS IN ANEUPLOID YEAST
Author(s) -
A. P. James,
Elizabeth R. Inhaber
Publication year - 1975
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/79.4.561
Subject(s) - meiosis , tetrad , homothallism , pairing , biology , genetics , chromosome , chromosome pairing , chromosomal crossover , ploidy , saccharomyces cerevisiae , chromosome segregation , aneuploidy , yeast , gene , physics , superconductivity , mating type , quantum mechanics
Meiotic pairing in homothallic S. cerevisiae was studied by tetrad analysis, using strains that were trisomic or tetrasomic for chromosome I. The disomic segregants of these strains produce tetrasomic spore colonies that can be distinguished by their phenotype. Results indicated the existence of preferential pairing and nonrandom assortment of chromosomes at meiosis I. The frequency of crossing over is apparently normal in at least some regions when non-preferred pairing occurs.

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