Open AccessRECESSIVE LETHAL AMBER SUPPRESSORS IN YEAST
Author(s) -
M C Brandriss,
Larry Soll,
David Botstein
Publication year - 1975
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/79.4.551
Subject(s) - biology , genetics , suppressor , dominant lethal , gene
Recessive lethal amber suppressor mutations have been isolated in a diploid strain of Saccharomyces cerevisiae. Diploids carrying these suppressors upon sporulation yield asci with only two live spores, both lacking the suppressor. At least two classes of recessive lethal suppressors exist. Aneuploid strains carrying one wild type and one suppressor locus have been isolated and used in mapping studies; one suppressor maps on chromosome III, the other does not.
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