THE RESPONSE OF DOPA DECARBOXYLASE ACTIVITY TO VARIATIONS IN GENE DOSAGE IN DROSOPHILA: A POSSIBLE LOCATION OF THE STRUCTURAL GENE
Author(s) -
Ross B. Hodgetts
Publication year - 1975
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/79.1.45
Subject(s) - gene duplication , biology , gene dosage , gene , genetics , chromosome , aromatic l amino acid decarboxylase , genome , drosophila (subgenus) , enzyme , gene expression , biochemistry
A location of the structural gene(s) for dopa decarboxylase (EC 4.1.1.26) is proposed on the basis of enzyme determinations in a set of duplication-bearing aneuploids, which revealed only one dosage-sensitive region in the Drosophila genome. This region lies between 36EF and 37D on the left arm of chromosome 2.
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