Open AccessTHE DNA OF CAENORHABDITIS ELEGANS
Author(s) -
John Sulston,
Sydney Brenner
Publication year - 1974
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/77.1.95
Subject(s) - biology , caenorhabditis elegans , rna , ploidy , genetics , genome , gene , dna , base pair , caenorhabditis , ribosomal rna
Chemical analysis and a study of renaturation kinetics show that the nematode, Caenorhabditis elegans, has a haploid DNA content of 8 x IO7 base pairs (20 times the genome of E. coli). Eighty-three percent of the DNA sequences are unique. The mean base composition is 36% GC; a small component, containing the rRNA cistrons, has a base composition of 51% GC. The haploid genome contains about 300 genes for 4s RNA, 110 for 5s RNA, and 55 for (18 + 28)S RNA.
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