UNSTABLE DIPLOIDS OF NEUROSPORA AND A MODEL FOR THEIR SOMATIC BEHAVIOR | Zendy

David A. Smith | Zendy

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UNSTABLE DIPLOIDS OF NEUROSPORA AND A MODEL FOR THEIR SOMATIC BEHAVIOR

Author(s) -

David A. Smith

Publication year - 1974

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/76.1.1

Subject(s) - biology , nondisjunction , loss of heterozygosity , genetics , ploidy , meiosis , neurospora , allele , somatic cell , chromosome , mitotic crossover , meiosis ii , homologous chromosome , chromosomal crossover , aneuploidy , neurospora crassa , gene , mutant

When ascospores from crosses of certain strains were germinated under conditions selective for heterozygosity of complementing markers on one linkage group, a portion of the resulting colonies were also heterozygous for unselected markers on other chromosomes, implying multiple disomy. The frequency of disomy and the pattern of marker homozygosity are consistent with most or all multiple disomics having originated as complete diploids following nondisjunction at meiosis I. The production of diploid ascospores in these strains is apparently under polygenic control. The diploids are highly unstable and do not differ from n+1 disomics in rates and mechanisms of haploidization and mitotic crossing over.

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