UV SENSITIVITY OF SEVERAL GENETIC MARKERS OF HAEMOPHILUS INFLUENZAE DNA | Zendy

M. R. Chevallier | Zendy; Marie-Louise Greth | Zendy

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UV SENSITIVITY OF SEVERAL GENETIC MARKERS OF HAEMOPHILUS INFLUENZAE DNA

Author(s) -

M. R. Chevallier,

Marie-Louise Greth

Publication year - 1973

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/74.3.405

Subject(s) - novobiocin , biology , genetic marker , genetics , haemophilus influenzae , dna , microbiology and biotechnology , gene , antibiotics

Studies on inactivation by UV of several genetic markers of the streptomycin and novobiocin resistance regions of H. influenzae DNA have shown that two kinds of markers may be found with respect to frequency of integration, UV sensitivity and reactivability. One class of markers has high integration frequency and low UV sensitivity, which can be partly explained by the reactivability of the irradiated markers. The second class of markers has low integration frequency and high UV sensitivity. Markers of each class have been found in the novobiocin region.-In one recipient strain with decreased transformability the difference in integration frequency between the two classes is enhanced.

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