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Correlation of the complementation relationships between the Notch locus alleles fag, fano, Ax59d and nd, with their genetic map order, suggests a tandem repetition within the locus of functionally related sites. This observation is discussed in relation to two hypotheses: (1) that the Notch locus contains a tandem repeat of genetic material; and (2) that the tertiary structure of the Notch locus product has a spiral configuration.

IS THE NOTCH LOCUS OF DROSOPHILA MELANOGASTER A TANDEM REPEAT? CORRELATION OF THE GENETIC MAP AND COMPLEMENTATION PATTERN OF SELECTED MUTATIONS