IS THE NOTCH LOCUS OF DROSOPHILA MELANOGASTER A TANDEM REPEAT? CORRELATION OF THE GENETIC MAP AND COMPLEMENTATION PATTERN OF SELECTED MUTATIONS | Zendy

G. G. Foster | Zendy

Open Access

IS THE NOTCH LOCUS OF DROSOPHILA MELANOGASTER A TANDEM REPEAT? CORRELATION OF THE GENETIC MAP AND COMPLEMENTATION PATTERN OF SELECTED MUTATIONS

Author(s) -

G. G. Foster

Publication year - 1973

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/73.3.435

Subject(s) - locus (genetics) , genetics , biology , complementation , drosophila melanogaster , allele , tandem repeat , gene , phenotype , genome

Correlation of the complementation relationships between the Notch locus alleles fag, fano, Ax59d and nd, with their genetic map order, suggests a tandem repetition within the locus of functionally related sites. This observation is discussed in relation to two hypotheses: (1) that the Notch locus contains a tandem repeat of genetic material; and (2) that the tertiary structure of the Notch locus product has a spiral configuration.

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