A Sod2 Null Mutation Confers Severely Reduced Adult Life Span in Drosophila | Zendy

Atanu Duttaroy | Zendy; Anirban Paul | Zendy; Mukta Kundu | Zendy; Amy Belton | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

A Sod2 Null Mutation Confers Severely Reduced Adult Life Span in Drosophila

Author(s) -

Atanu Duttaroy,

Anirban Paul,

Mukta Kundu,

Amy Belton

Publication year - 2003

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/165.4.2295

Subject(s) - sod2 , biology , drosophila melanogaster , genetics , null allele , heterozygote advantage , phenotype , mutation , gene , drosophilidae , oxidative stress , genotype , superoxide dismutase , endocrinology

A null mutation for the Sod2 gene, Sod2n283, was obtained in Drosophila melanogaster. Homozygous Sod2 null (Sodn283/Sodn283) adult flies survive up to 24 hr following eclosion, a phenotype reminiscent of mice, where Sod2–/– progeny suffer neonatal lethality. Sodn283/+ heterozygotes are sensitive to oxidative stress induced by paraquat treatment.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research