A Function for Subtelomeric DNA in Saccharomyces cerevisiae | Zendy

Arnold B. Barton | Zendy; Yuping Su | Zendy; Jacque Lamb | Zendy; D. L. Barber | Zendy; David B. Kaback | Zendy

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A Function for Subtelomeric DNA in Saccharomyces cerevisiae

Author(s) -

Arnold B. Barton,

Yuping Su,

Jacque Lamb,

D. L. Barber,

David B. Kaback

Publication year - 2003

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/165.2.929

Subject(s) - subtelomere , biology , saccharomyces cerevisiae , genetics , meiosis , telomere , homologous recombination , recombination , chromosome , genetic recombination , dna , gene

The subtelomeric DNA sequences from chromosome I of Saccharomyces cerevisiae are shown to be inherently poor substrates for meiotic recombination. On the basis of these results and prior observations that crossovers near telomeres do not promote efficient meiosis I segregation, we suggest that subtelomeric sequences evolved to prevent recombination from occurring where it cannot promote efficient segregation.

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