Invasive Filamentous Growth of Candida albicans Is Promoted by Czf1p-Dependent Relief of Efg1p-Mediated Repression | Zendy

Angela D. Giusani | Zendy; Marcelo D. Vinces | Zendy; Carol A. Kumamoto | Zendy

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Invasive Filamentous Growth of Candida albicans Is Promoted by Czf1p-Dependent Relief of Efg1p-Mediated Repression

Author(s) -

Angela D. Giusani,

Marcelo D. Vinces,

Carol A. Kumamoto

Publication year - 2002

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/160.4.1749

Subject(s) - filamentation , psychological repression , candida albicans , biology , corpus albicans , microbiology and biotechnology , genetics , function (biology) , gene , gene expression , laser , physics , optics

Filamentation of Candida albicans occurs in response to many environmental cues. During growth within matrix, Efg1p represses filamentation and Czf1p relieves this repression. We propose that Czf1p interacts with Efg1p, altering its function. The complex regulation of filamentation may reflect the versatility of C. albicans as a pathogen.

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