Open AccessGenetic and cytogenetic analysis of the 43A-E region containing the segment polarity gene costa and the cellular polarity genes prickle and spiny-legs in Drosophila melanogaster.
Author(s) -
Pascal Heitzler,
Darin Coulson,
Maria Teresa Sáenz-Robles,
Michael Ashburner,
John Roote,
Patricia Simpson,
David Gubb
Publication year - 1993
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/135.1.105
Subject(s) - biology , complementation , genetics , drosophila melanogaster , locus (genetics) , gene , melanogaster , gene mapping , phenotype , drosophilidae , chromosome , chromosomal region
A cytogenetic analysis of the 43A-E region of chromosome 2 in Drosophila melanogaster is presented. Within this interval 27 complementation groups have been identified by extensive F2 screens and ordered by deletion mapping. The region includes the cellular polarity genes prickle and spiny-legs, the segmentation genes costa and torso, the morphogenetic locus sine oculis and is bounded on its distal side by the eye-color gene cinnabar. In addition 19 novel lethal complementation groups and two semi-lethal complementation groups with morphogenetic escaper phenotypes are described.
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