Linkage disequilibrium analysis of chromosomal inversion polymorphisms of Drosophila.
Author(s) -
Alexandre A. Peixoto,
Louis Bernard Klaczko
Publication year - 1991
Publication title -
genetics.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
ISSN - 3049-7094
DOI - 10.1093/genetics/129.3.773
Subject(s) - linkage disequilibrium , biology , disequilibrium , chromosomal inversion , genetics , linkage (software) , drosophila (subgenus) , drosophila subobscura , evolutionary biology , selection (genetic algorithm) , computational biology , haplotype , chromosome , karyotype , genotype , computer science , artificial intelligence , gene , medicine , ophthalmology
The linkage disequilibrium pattern analysis is a method that allows one to detect present and past events of selection. We applied it to our data on the inversions of Drosophila mediopunctata and to published data of Drosophila subobscura, which are systems probably under complex modes of selection. The method gave meaningful results showing that it might be an excellent exploratory tool to identify problems worthy of further study. It is also suggested that it can be used as a criterion to determine the roots of inversion phylogenies.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom