Seven-base-pair inverted repeats in DNA form stable hairpins in vivo in Saccharomyces cerevisiae. | Zendy

Dilip K. Nag | Zendy; Thomas D. Petes | Zendy

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Seven-base-pair inverted repeats in DNA form stable hairpins in vivo in Saccharomyces cerevisiae.

Author(s) -

Dilip K. Nag,

Thomas D. Petes

Publication year - 1991

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/129.3.669

Subject(s) - palindrome , saccharomyces cerevisiae , biology , base pair , genetics , inverted repeat , palindromic sequence , dna , direct repeat , in vivo , yeast , base sequence , gene , genome

Palindromic sequences in single-stranded DNA and RNA have the potential for intrastrand base pairing, resulting in formation of "hairpin" structures. We previously reported a genetic method for detecting such structures in vivo in the yeast Saccharomyces cerevisiae. Below, we describe evidence indicating that a 14-base-pair palindrome (7 bp per inverted repeat) is sufficient for formation of a hairpin in vivo.

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