Aristapedioid: a gain of function, homeotic mutation in Drosophila melanogaster. | Zendy

Brian P. Brunk | Zendy; Paul N. Adler | Zendy

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Aristapedioid: a gain of function, homeotic mutation in Drosophila melanogaster.

Author(s) -

Brian P. Brunk,

Paul N. Adler

Publication year - 1990

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/124.1.145

Subject(s) - biology , genetics , homeotic gene , drosophila melanogaster , bristle , chromosomal inversion , mutation , gene , phenotype , function (biology) , chromosome , karyotype , brush , electrical engineering , engineering

The isolation of gain of function mutations has allowed the identification of a number of genes which are important in the normal development of the organism. We report here the isolation and characterization of Aristapedioid, a gain of function mutation which causes a partial transformation of arista towards tarsus and the loss or decrease in size of the dorso-central and scutellar bristles. Aristapedioid is the result of a P element mediated inversion which juxtaposes unrelated DNA adjacent to Suppressor 2 of zeste, causing a gain of function mutation in that gene.

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