Analysis of yeast retrotransposon Ty insertions at the CAN1 locus. | Zendy

Cailin Moira Wilke | Zendy; Steven Heidler | Zendy; Nicola J. Brown | Zendy; Susan W. Liebman | Zendy

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Analysis of yeast retrotransposon Ty insertions at the CAN1 locus.

Author(s) -

Cailin Moira Wilke,

Steven Heidler,

Nicola J. Brown,

Susan W. Liebman

Publication year - 1989

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/123.4.655

Subject(s) - biology , genetics , retrotransposon , locus (genetics) , saccharomyces cerevisiae , gene , transposable element , genome

The target site distribution for 55 independent Ty insertions that inactivate the function of the Saccharomyces cerevisiae CAN1 gene is reported. Under some selection conditions Ty elements inserted preferentially into the promoter and exhibited an orientation bias. In contrast, under other conditions no insertions were detected in the promoter region and transposition appeared to occur randomly throughout the CAN1 coding sequence. These results show that the target site distribution for Ty insertions may be a function of the selection conditions.

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