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A cytogenetic analysis of the Punch-tudor region of chromosome 2R in Drosophila melanogaster.
Author(s) -
Janis M. O’Donnell,
Robert Boswell,
Thomas Reynolds,
William J. Mackay
Publication year - 1989
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/121.2.273
Subject(s) - biology , genetics , complementation , locus (genetics) , allele , drosophila melanogaster , chromosome , phenotype , mutagenesis , mutation , microbiology and biotechnology , gene
Eleven chromosomal deficiencies and several rearrangements in the Pu-tud region of chromosome 2R have been generated and examined cytologically. The Pu locus has been localized to chromosome bands 57C5-6 and tud to 57C7-8. Mutagenesis within the region defined by the deletion intervals has resulted in the isolation of 92 new lethal mutations. Seventy-six of these mutations have been separated into 16 complementation groups that have been ordered and placed cytologically by deletion mapping. All new alleles fully complement tud for both lethal and grandchildless phenotypes. The largest number of new mutations, a total of 25, are Pu alleles.

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