GENETIC CONTROLS OVER ACTIVITIES OF TYROSINASE AND DOPACHROME CONVERSION FACTOR IN MURINE MELANOCYTES | Zendy

M. Lynn Lamoreux | Zendy; Catherine S. Woolley | Zendy; Phil Pendergast | Zendy

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GENETIC CONTROLS OVER ACTIVITIES OF TYROSINASE AND DOPACHROME CONVERSION FACTOR IN MURINE MELANOCYTES

Author(s) -

M. Lynn Lamoreux,

Catherine S. Woolley,

Phil Pendergast

Publication year - 1986

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/113.4.967

Subject(s) - tyrosinase , biology , genetics , gene , enzyme , biochemistry

We evaluated the three catalytic activities of tyrosinase and one activity of dopachrome conversion factor (DCF) in extracts made from skins of 6-day-old yellow and nonyellow mice. At least one of the catalytic activities of tyrosinase and of DCF correlate with the color of pigment being produced in the hair follicles of the mice. We use these data to evaluate existing hypotheses about the mechanism of the interacting genetic controls over melanogenesis.

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