MOLECULAR MAPPING OF THE ROSY LOCUS IN DROSOPHILA MELANOGASTER
Author(s) -
Babette D. Cote,
Welcome Bender,
Daniel Curtis,
Arthur Chovnick
Publication year - 1986
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/112.4.769
Subject(s) - biology , locus (genetics) , genetics , drosophila melanogaster , allele , dna , mutant , recombination , gene
The DNA from the chromosomal region of the Drosophila rosy locus has been examined in 83 rosy mutant strains. Several spontaneous and radiation-induced alleles were associated with insertions and deletions, respectively. The lesions are clustered in a 4-kb region. Some of the alleles identified on the DNA map have been located on the genetic map by fine-structure recombination experiments. The genetic and molecular maps are collinear, and the alignment identifies the DNA location of the rosy control region. A rosy RNA of 4.5 kb has been identified; its 5' end lies in or near the control region.
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